A multicenter dose response study of sustained release diltiazem hydrochloride in angina pectoris
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چکیده
منابع مشابه
C-REACTIVE PROTEIN RESPONSE IN ANGINA PECTORIS
C-reactive protein (CRP) response was studied in 44 patients with acute angina pectoris admitted to the coronary care unit. 71 % of patients with acute myocardial infarction (MI)had positive CRP test while 73% of patients presumed to have unstable angina pectoris had negative CRP test. This test can be helpful in differentiating between acute MI and unstable angina pectoris.
متن کاملDouble-blind, dose-response, placebo-controlled multicenter study of nisoldipine. A new second-generation calcium channel blocker in angina pectoris.
BACKGROUND Nisoldipine is a potent 1:4 dihydropyridine calcium channel antagonist, and doses of 5 or 10 mg administered either once or twice daily have been claimed to exert antianginal effects. There is, however, little information regarding the dose-response relation and whether the drug exerts any consistent effects throughout the dosing interval. In this placebo-controlled, parallel-design ...
متن کاملIn vitro Release Kinetics Study of Diltiazem Hydrochloride from Wax and Kollidon SR Based Matrix Tablets
Extended-release matrix tablets of diltiazem hydrochloride (DTZ) were prepared using waxy materials alone or in combination with Kollidon SR. Matrix waxy materials were carnauba wax (CW), bees wax (BW), cetyl alcohol (CA) and glyceryl monostearate (GMS). Dissolution studies were carried out by using a six stations USP XXII type 1 apparatus. The in vitro drug release study was done in 1000 ml ph...
متن کاملIn vitro Release Kinetics Study of Diltiazem Hydrochloride from Wax and Kollidon SR Based Matrix Tablets
Extended-release matrix tablets of diltiazem hydrochloride (DTZ) were prepared using waxy materials alone or in combination with Kollidon SR. Matrix waxy materials were carnauba wax (CW), bees wax (BW), cetyl alcohol (CA) and glyceryl monostearate (GMS). Dissolution studies were carried out by using a six stations USP XXII type 1 apparatus. The in vitro drug release study was done in 1000 ml ph...
متن کاملCombination treatment with trimetazidine and diltiazem in stable angina pectoris.
OBJECTIVE To assess antianginal efficacy and possible adverse haemodynamic effects of combination treatment with trimetazidine and diltiazem in patients with stable angina. DESIGN Double blind, randomised, placebo controlled trial of four weeks duration. SETTING Outpatient department of two Indian hospitals. SUBJECTS 64 male patients with stable angina, uncontrolled on diltiazem alone. ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1990
ISSN: 0735-1097
DOI: 10.1016/0735-1097(90)92406-r